dN/dS Calculator
Calculate synonymous and nonsynonymous substitution rates to detect selection.
Substitution Data
Synonymous (Silent)
Nonsynonymous (Replacement)
Interpretation
- omega < 1: Purifying selection
- omega = 1: Neutral evolution
- omega > 1: Positive selection
dN/dS Ratio (omega)
0.6589
omega = dN / dS
Weak purifying selection
Selection Analysis
↓
Purifying Selection
Substitution Rates
dS (synonymous)0.051745
dN (nonsynonymous)0.034097
Raw Data
pS (proportion)0.050000
pN (proportion)0.033333
Syn. Rate (×10⁻⁹/yr)2587232.6808
Nonsyn. Rate (×10⁻⁹/yr)1704839.0279
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Editorial Note
MyCalcBuddy Editorial Team
This page is maintained as an educational calculator reference.
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Formula Source: Standard Mathematical References
by Various
🔄Last reviewed: May 2026
✓Formula checks are based on standard references and internal QA review.