Anion Gap Calculator

Calculate the anion gap from serum electrolytes to help diagnose metabolic acidosis and other acid-base disorders.

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Important Health Disclaimer

This calculator provides general health information based on standard medical formulas and WHO guidelines. Results are for informational and educational purposes only and should not be considered as professional medical advice, diagnosis, or treatment recommendations.

For health concerns, medical conditions, fitness plans, or dietary decisions, please consult with qualified healthcare professionals, licensed physicians, registered dietitians, or certified fitness trainers who can evaluate your individual health status and medical history.

Individual health needs vary significantly. These calculations are general estimates and may not be appropriate for everyone, especially those with existing medical conditions, pregnant women, children, or elderly individuals.

Not a substitute for professional medical advice

Serum Electrolytes

mEq/L

Normal: 136-145 mEq/L

mEq/L

Normal: 98-106 mEq/L

mEq/L

Normal: 22-26 mEq/L

g/dL

For albumin-corrected AG (Normal: 3.5-5.0 g/dL)

Anion Gap

14.0 mEq/L

High Anion Gap

🧪Standard AG
14.0 mEq/L
📊Corrected AG
14.0 mEq/L
📈Delta Ratio
N/A
Normal Range
8-12 mEq/L

Interpretation

Metabolic acidosis with increased anion gap (HAGMA)

Causes of Abnormal Anion Gap

High Anion Gap (MUDPILES)

  • Methanol
  • Uremia
  • Diabetic ketoacidosis
  • Propylene glycol
  • Isoniazid, Iron
  • Lactic acidosis
  • Ethylene glycol
  • Salicylates

Low Anion Gap

  • Hypoalbuminemia
  • Multiple myeloma (paraproteins)
  • Lithium toxicity
  • Bromide ingestion
  • Laboratory error
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sources

  • World Health Organization (WHO) — Global health metrics, disease classification, and nutritional standards. who.int
  • Centers for Disease Control and Prevention (CDC) — Health statistics, BMI guidelines, and disease prevention data. cdc.gov
  • National Institutes of Health (NIH) — Medical research, clinical guidelines, and health calculators. nih.gov
  • Mayo Clinic — Clinical health information, disease reference, and wellness guidance. mayoclinic.org

For a complete list of all references used across the site, visit our full sources page.

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Editorial Note

MyCalcBuddy Editorial Team

This page is maintained as an educational calculator reference.

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Formula Source: WHO Health Metrics Standards

by World Health Organization

🔄Last reviewed: May 2026
✓Formula checks are based on standard references and internal QA review.