Renal Drug Dosage Calculator
Adjust drug dosages based on kidney function using creatinine clearance and various adjustment methods.
Patient Information
years
Drug Parameters
mg
Standard dose for normal renal function
hours
Creatinine Clearance (CrCl)
48.6 mL/min
Moderate reduction (CKD Stage 3)
🏥Renal Stage
Moderate
📊Adjustment Factor
75%
💊Adjusted Dose
375 mg
⏱️Extended Interval
10.7 hrs
Adjustment Options
Dose Reduction: 375 mg every 8 hours
Interval Extension: 500 mg every 10.7 hours
Combined: 433 mg every 9.2 hours
Daily Dose Comparison
Normal daily dose: 1500 mg/day
Adjusted daily dose: 1125 mg/day
Clinical Warning
This is a general guide. Actual dose adjustments vary by drug. Always consult current drug references and consider other patient factors including dialysis status.
CKD Staging & Dosing Guide
| CKD Stage | GFR/CrCl (mL/min) | Description | Typical Adjustment |
|---|---|---|---|
| Stage 1 | ≥90 | Normal function | No adjustment |
| Stage 2 | 60-89 | Mild reduction | No adjustment usually |
| Stage 3a | 45-59 | Mild-moderate reduction | Consider adjustment |
| Stage 3b | 30-44 | Moderate-severe reduction | 25-50% dose reduction |
| Stage 4 | 15-29 | Severe reduction | 50-75% dose reduction |
| Stage 5 | < 15 | Kidney failure/ESRD | 75%+ reduction, consider dialysis |