Allosteric Cooperativity Calculator
Analyze allosteric cooperativity using the Monod-Wyman-Changeux (MWC) concerted model
MWC Model Parameters
Ratio of T to R state in absence of ligand
Fractional Saturation
45.31%
R State (Active)
51.60%
T State (Inactive)
48.40%
Apparent Hill Coefficient
3.009
Cooperativity Index
0.9990
Equilibrium State
Favors T state at low [S]
MWC Model
The concerted model assumes all subunits exist in either R (relaxed, high affinity) or T (tense, low affinity) states, with transitions occurring simultaneously.
💡
Help us improve!
How would you rate the Allosteric Cooperativity Calculator?
Editorial Note
MyCalcBuddy Editorial Team
This page is maintained as an educational calculator reference.
📚
Formula Source: Standard Mathematical References
by Various
🔄Last reviewed: May 2026
✓Formula checks are based on standard references and internal QA review.