Circular Dichroism Calculator
Calculate mean residue ellipticity and estimate protein secondary structure
Sample Parameters
Secondary Structure Analysis
Mean Residue Ellipticity
-16500000
deg cm² dmol⁻¹ residue⁻¹
Calculated Values
Mean Residue Weight110.0 Da
[θ]MRW-16500000
Secondary Structure Estimate
α-Helix74.4%
β-Sheet15.6%
Random Coil10.0%
Note
Secondary structure estimates are approximate. For accurate analysis, use specialized software like CDNN, K2D, or BeStSel with full spectral data.
About Circular Dichroism
Circular dichroism measures the differential absorption of left- and right-circularly polarized light. Key features:
- α-helix: Negative bands at 222nm and 208nm, positive band at 193nm
- β-sheet: Negative band at ~218nm, positive band at ~195nm
- Random coil: Negative band near 198nm
- Applications: Protein folding, stability, conformational changes
Formula: [θ]MRW = (θ × MRW) / (10 × c × l)