Hepatic Dosing Calculator
Calculate medication dose adjustments for patients with liver disease using Child-Pugh scoring and hepatic extraction considerations.
Child-Pugh Parameters
mg/dL
Normal: <1.2 mg/dL
g/dL
Normal: 3.5-5.0 g/dL
Normal: 0.9-1.1
Drug Information
mg
Child-Pugh Score
6 (Class A)
Well-compensated
💊Adjusted Dose
375 mg
📉Dose Reduction
25%
📊Adjustment Factor
75%
📈1-Year Survival
100%
Score Components
Bilirubin: 1 point(s)
Albumin: 2 point(s)
INR: 1 point(s)
Ascites: 1 point(s)
Encephalopathy: 1 point(s)
Recommendation
Mild impairment - may need minor adjustment for high-extraction drugs
Child-Pugh Classification
| Class | Score | Severity | Dose Adjustment |
|---|---|---|---|
| A | 5-6 | Mild | Usually none needed |
| B | 7-9 | Moderate | 50-75% of normal |
| C | 10-15 | Severe | 25-50% of normal |